According to Medical News Today, a new study had been done regarding growths in the brain with mice. These creatures have been utilized in brain tumor research efforts before, of course, and some of the finest results have come to the surface. When there are efforts seen amongst these mice, it is very likely that humans will be able to benefit from them in some way or another. I believe this to be the case after reading up on the results that came from this particular study.
It's apparent that the John Hopkins University School of Medicine has been able to utilize a particular drug, bringing it into strong effect. The drug was referred to as 5-azacytidine, which is something that could prove useful in brain tumor research given the fact that it has been utilized in the past. More specifically, it had an effect on pre-leukemia, so it's clear that there's reliability to be seen. It's just a matter of seeing if it will play into the focus of organizations the likes of Voices against Brain Cancer.
The drug in question was said to be able to target a certain aspect of gliomas; these are the most common, aggressive types of growths seen in the brain. They would focus on IDH1, which was uncovered during 2008 by those in the same university. It's a mutation that is found in a great amount of lower-grade tumors, about 70 to 80 percent to be more specific. With such an alteration set in place, the protein cannot process glucose, meaning energy cannot be attained.
During the study in question, 5-azacytidine was done through mice and the study lasted a total of 14 weeks. The end of the study showed that tumor growth went down quite a bit and a relapse had not been seen since that point. In fact, once usage of the drug stopped, the tumors that the mice had did not come back after seven weeks. I think that this is very telling, especially when tumors have a difficult time responding to tumors for the sake of regression.
Researchers typically do not expect to see tumor regression, which speaks volumes about how strong this study was in the realm of brain tumor research. These findings could prove useful in the future if the mice utilized have seen positive results. Is it possible that humans will be able to benefit from such processes in the long term as well? I like to think that this will be the case but it is just a matter of time as potential work will be gone about.
It's apparent that the John Hopkins University School of Medicine has been able to utilize a particular drug, bringing it into strong effect. The drug was referred to as 5-azacytidine, which is something that could prove useful in brain tumor research given the fact that it has been utilized in the past. More specifically, it had an effect on pre-leukemia, so it's clear that there's reliability to be seen. It's just a matter of seeing if it will play into the focus of organizations the likes of Voices against Brain Cancer.
The drug in question was said to be able to target a certain aspect of gliomas; these are the most common, aggressive types of growths seen in the brain. They would focus on IDH1, which was uncovered during 2008 by those in the same university. It's a mutation that is found in a great amount of lower-grade tumors, about 70 to 80 percent to be more specific. With such an alteration set in place, the protein cannot process glucose, meaning energy cannot be attained.
During the study in question, 5-azacytidine was done through mice and the study lasted a total of 14 weeks. The end of the study showed that tumor growth went down quite a bit and a relapse had not been seen since that point. In fact, once usage of the drug stopped, the tumors that the mice had did not come back after seven weeks. I think that this is very telling, especially when tumors have a difficult time responding to tumors for the sake of regression.
Researchers typically do not expect to see tumor regression, which speaks volumes about how strong this study was in the realm of brain tumor research. These findings could prove useful in the future if the mice utilized have seen positive results. Is it possible that humans will be able to benefit from such processes in the long term as well? I like to think that this will be the case but it is just a matter of time as potential work will be gone about.
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